Intern Med. 2024 Aug 28. doi: 10.2169/internalmedicine.4124-24. Online ahead of print.
ABSTRACT
A 58-year-old woman was admitted to our hospital with anasarca and generalized lymphadenopathy. Laboratory data showed serum Cr 1.48 mg/dL, CRP 2.38 mg/dL, PLT 102,000/μL, and anti-SS-A antibodies (SS-A-ab). A lymph node biopsy revealed a regressed germinal center and hypervascularization in the interfollicular area. The patient was diagnosed with TAFRO-like symptoms occurring with Sjögren’s syndrome and HTLV-1 infection, and 80 mg of methylprednisolone and tocilizumab 8 mg/kg biweekly were initiated. Her body weight decreased from 59.4 to 41 kg, and pleural effusion disappeared 8 weeks later. This case suggests that TAFRO-like symptoms may occur in patients with Sjögren’s syndrome with HTLV-1 infection.
PMID:39198166 | DOI:10.2169/internalmedicine.4124-24
