Adult T-cell leukemia/lymphoma complicated by Pneumocystis pneumonia in a non-endemic area

by | Jan 20, 2023 | Publications

Respir Med Case Rep. 2023 Jan 4;42:101807. doi: 10.1016/j.rmcr.2023.101807. eCollection 2023.

ABSTRACT

Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus type 1-inducing unevenly-distributed T-cell malignancy, which is often complicated by opportunistic infections. Here, we discuss the case of a 75-year-old woman presenting with Pneumocystis pneumonia (PCP) who was subsequently diagnosed with ATLL in Tokyo, a non-endemic area of ATLL. In addition to the elevated soluble interleukin-2 receptor and the detection of flower cells in the screening blood test, the high-resolution computed tomography findings, atypical of PCP, were clues to the diagnosis of ATLL. ATLL should be considered as an underlying disease when patients present with PCP, even in non-endemic areas.

PMID:36660069 | PMC:PMC9843483 | DOI:10.1016/j.rmcr.2023.101807

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