by | May 4, 2023 | Publications
Blood Cancer J. 2023 May 3;13(1):67. doi: 10.1038/s41408-023-00841-7. ABSTRACT Adult T cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax initiates T cell...
by | May 1, 2023 | Publications
J Virol. 2023 May 1:e0036123. doi: 10.1128/jvi.00361-23. Online ahead of print. ABSTRACT Several recent studies indicate that mutations in the human immunodeficiency virus type 1 (HIV-1) 3’polypurine tract (3’PPT) motif can reduce sensitivity to the...
by | May 1, 2023 | Publications
Rinsho Ketsueki. 2023;64(4):283-289. doi: 10.11406/rinketsu.64.283. ABSTRACT A 55-year-old male was referred to our hospital after complaining of a sore throat for a month. Physical examination revealed a disturbance in consciousness, nuchal rigidity, painful multiple...
by | Apr 28, 2023 | Publications
Curr Comput Aided Drug Des. 2023 Apr 19. doi: 10.2174/1573409919666230419082839. Online ahead of print. ABSTRACT INTRODUCTION: Integration of viral DNA into the host cell genome, carried out by the HTLV-1 integrase enzyme, is a crucial step in the Human T-lymphotropic...
by | Apr 28, 2023 | Publications
Int J Mol Sci. 2023 Apr 9;24(8):6961. doi: 10.3390/ijms24086961. ABSTRACT The perception of human T-cell leukemia virus type 1 (HTlV-1) infection as a “silent disease” has recently given way to concern that its presence may be having a variety of effects....
by | Apr 28, 2023 | Publications
Pharmaceuticals (Basel). 2023 Mar 23;16(4):485. doi: 10.3390/ph16040485. ABSTRACT Approximately 20% of all cases of human cancer are caused by viral infections. Although a great number of viruses are capable of causing a wide range of tumors in animals, only seven of...
