Decoding pathogenesis factors

Decoding pathogenesis factors

Decoding pathogenesis factors involved in the progression of ATLL or HAM/TSP after infection by HTLV-1 through a systems virology study Abstract Background: Human T-cell Leukemia Virus type-1 (HTLV-1) is a retrovirus that causes two diseases including Adult T-cell...
Decoding pathogenesis factors

HTLV-1 Disease

HTLV-1 Disease Abstract The years 2020 and 2021 will remain memorable years for many reasons […]. Click here to access the publication.
Decoding pathogenesis factors

An Epitope Platform for Safe and Effective HTLV-1-Immunization

An Epitope Platform for Safe and Effective HTLV-1-Immunization: Potential Applications for mRNA and Peptide-Based Vaccines Abstract Human T-cell lymphotropic virus type 1 (HTLV-1) infection affects millions of individuals worldwide and can lead to severe leukemia,...
Decoding pathogenesis factors

Involvement of EZH2 inhibition in lenalidomide and pomalidomide

Involvement of EZH2 inhibition in lenalidomide and pomalidomide-mediated growth suppression in HTLV-1-infected cells Abstract Immunomodulatory imide drugs (IMiDs), such as lenalidomide and pomalidomide, exert pleiotropic effects, e.g., antitumor effects in multiple...
Decoding pathogenesis factors

Polymorphisms in HTLV-1

Polymorphisms in HTLV-1 Tax-responsive elements in HTLV-1-associated myelopathy/tropical spastic paraparesis patients are associated with reduced proviral load but not with disease progression Abstract Human T-lymphotropic virus type 1 (HTLV-1) provirus expression is...