Three cases of acute retinal necrosis with atypical fundus findings

by | Feb 3, 2023 | Publications

Retin Cases Brief Rep. 2022 Nov 18. doi: 10.1097/ICB.0000000000001379. Online ahead of print.


PURPOSE: To determine the mechanism for the development of segmental granular lesions along the retinal vessels in eyes with acute retinal necrosis (ARN).

METHOD: This was a retrospective analysis of the medical records of 3 eyes of 3 patients who were diagnosed with ARN that had atypical segmental granular lesions aligned along the retinal vessels.

RESULTS: The segmental granular lesions were present on both the retinal arteries and veins throughout the retina. Optical coherence tomography (OCT) showed that the granular lesions protruded into the vitreous cavity. Histopathological examinations confirmed that the lesions were made up of lymphocytes.

CONCLUSIONS: We suggest that the granular lesions were formed by a mechanism similar to that of HTLV-1-associated uveitis (HAU). We also found that the granular lesions disappeared soon after vitrectomy.

PMID:36730471 | DOI:10.1097/ICB.0000000000001379

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